SCHEMBL25864503 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	3/20	0.39

▸	MAPT	P10636	6/20	0.38

▸	TP53	P04637	2/20	0.38

▸	KDM4E	B2RXH2	2/20	0.37

▸	HSD17B10	Q99714	1/20	0.37

▸	LMNA	P02545	2/20	0.37

▸	GAA	P10253	4/20	0.35

▸	KMT2A	Q03164	2/20	0.35

▸	HTT	P42858	1/20	0.35

▸	ENPP3	O14638	1/20	0.35

▸	NPSR1	Q6W5P4	4/20	0.35

▸	HPGD	P15428	1/20	0.35

▸	KDR	P35968	2/20	0.35

▸	MEN1	O00255	1/20	0.34

▸	PKM	P14618	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25855978	0.87	ALDH1A1 (0.43)	ALDH1A1MAPTTP53KDM4EHSD17B10
SCHEMBL25862285	0.87	ALDH1A1 (0.43)	ALDH1A1MAPTTP53KDM4EHSD17B10
SCHEMBL25301909	0.87	ALDH1A1 (0.43)	ALDH1A1MAPTTP53KDM4EHSD17B10
SCHEMBL25864241	0.85	KDM4E (0.34)	ALDH1A1MAPTTP53KDM4EHSD17B10
SCHEMBL25864303	0.85	KDM4E (0.36)	ALDH1A1MAPTTP53KDM4EHSD17B10
SCHEMBL25864505	0.85	NLRP3 (0.37)	ALDH1A1MAPTTP53KDM4EHSD17B10
SCHEMBL25864504	0.84	NLRP3 (0.35)	ALDH1A1KDM4EHSD17B10LMNAGAA
SCHEMBL25864507	0.82	NLRP3 (0.41)	ALDH1A1KDM4EHSD17B10LMNAGAA
SCHEMBL25864065	0.82	NLRP3 (0.48)	—
SCHEMBL26116190	0.74	MAPT (0.55)	ALDH1A1MAPTTP53LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023131277-A1	NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF	药捷安康(南京)科技股份有限公司	2023-07-13	—	—	WO	disclosed