Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26475369 | 0.87 | HTT (0.50) | LMNAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL8004911 | 0.83 | LMNA (0.52) | LMNAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL13745751 | 0.83 | HTT (0.55) | LMNAALDH1A1USP2KMT2AMEN1 | |
| SCHEMBL12038511 | 0.80 | KDM4E (0.38) | LMNAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL12424259 | 0.80 | NAMPT (0.45) | LMNAALDH1A1USP2KMT2AMEN1 | |
| SCHEMBL24204513 | 0.79 | ALDH1A1 (0.47) | LMNAALDH1A1USP2KMT2AMEN1 | |
| SCHEMBL10039301 | 0.78 | HPGD (0.60) | LMNAALDH1A1USP2KMT2AMEN1 | |
| SCHEMBL24185788 | 0.77 | KDM4E (0.43) | LMNAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL24480430 | 0.77 | HPGD (0.58) | LMNAALDH1A1USP2KMT2AMEN1 | |
| SCHEMBL26475374 | 0.77 | KDM4E (0.36) | LMNAALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |