Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 4/20 | 0.56 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | BRAF | P15056 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25856348 | 0.89 | MAPT (0.48) | RAF1PRKD1MAPTTP53PARP1 | |
| SCHEMBL25308786 | 0.84 | MAPT (0.57) | RAF1PRKD1MAPTTP53PARP1 | |
| SCHEMBL9958168 | 0.77 | KDM4E (0.59) | MAPTTP53PARP1KDM4ETDP1 | |
| SCHEMBL25309227 | 0.74 | MAPT (0.58) | RAF1MAPTTP53PARP1 | |
| SCHEMBL25262291 | 0.74 | ABL1 (0.49) | RAF1PRKD1MAPTTP53PARP1 | |
| SCHEMBL25306725 | 0.74 | MAPT (0.53) | RAF1MAPTTP53KDM4EROCK1 | |
| SCHEMBL10887525 | 0.72 | MAPT (0.54) | MAPTTP53 | |
| SCHEMBL29033904 | 0.71 | RAF1 (0.57) | RAF1PRKD1BRAF | |
| SCHEMBL25856272 | 0.69 | MAPT (0.50) | PRKD1MAPTTP53TDP1 | |
| SCHEMBL31660247 | 0.69 | APP (0.60) | RAF1MAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130540-A1 | PYRAZOL BENZAMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州大学 | 2023-07-13 | — | — | WO | disclosed |