Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.46 |
| ▸ | ACP1 | P24666 | 2/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25856271 | 0.89 | RAF1 (0.56) | MAPTKDM4EPRKD1RAF1TP53 | |
| SCHEMBL25306725 | 0.85 | MAPT (0.53) | MAPTRAB9AKDM4EMEN1KMT2A | |
| SCHEMBL9976034 | 0.74 | RAB9A (0.77) | MAPTNPC1MAPK1RAB9AKDM4E | |
| SCHEMBL25308786 | 0.74 | MAPT (0.57) | MAPTNPC1RAB9ASMN1; SMN2PRKD1 | |
| SCHEMBL22307585 | 0.74 | RAB9A (0.81) | MAPTNPC1MAPK1RAB9AKDM4E | |
| SCHEMBL29033894 | 0.73 | MAPT (0.53) | MAPTNPC1MAPK1RAB9AKDM4E | |
| SCHEMBL25262291 | 0.72 | ABL1 (0.49) | MAPTPRKD1RAF1TP53PARP1 | |
| SCHEMBL25309227 | 0.72 | MAPT (0.58) | MAPTNPC1RAB9ASMN1; SMN2RAF1 | |
| SCHEMBL1181118 | 0.72 | RAB9A (0.77) | MAPTNPC1MAPK1RAB9AKDM4E | |
| SCHEMBL17279790 | 0.72 | RAB9A (0.77) | MAPTNPC1MAPK1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130540-A1 | PYRAZOL BENZAMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州大学 | 2023-07-13 | — | — | WO | disclosed |