Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317237 | 0.85 | CYP1A2 (0.33) | CYP1A2CYP2D6ALOX15OPRM1OPRK1 | |
| SCHEMBL25856192 | 0.82 | CYP1A2 (0.41) | CYP1A2CYP2D6ALOX15OPRM1OPRK1 | |
| SCHEMBL17471124 | 0.80 | GNAO1 (0.41) | ACHEGNAO1GBA1HTR4 | |
| SCHEMBL24480580 | 0.77 | GNAO1 (0.34) | ACHEGNAO1CHRM3GBA1 | |
| SCHEMBL25856392 | 0.76 | GBA1 (0.34) | ACHEGNAO1OPRM1OPRL1GBA1 | |
| SCHEMBL25518226 | 0.74 | HTR6 (0.41) | CYP1A2CYP2D6ALOX15OPRM1OPRK1 | |
| SCHEMBL25856205 | 0.74 | GBA1 (0.35) | CYP2D6GBA1 | |
| SCHEMBL24480318 | 0.73 | GNAO1 (0.35) | CYP2D6ACHEGNAO1OPRM1OPRD1 | |
| SCHEMBL24196541 | 0.73 | CHRM5 (0.48) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL24480701 | 0.72 | GBA1 (0.40) | GNAO1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |