Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25856192 | 0.90 | CYP1A2 (0.41) | CYP1A2CYP2D6ALOX15OPRM1OPRK1 | |
| SCHEMBL25027108 | 0.85 | ACHE (0.38) | GBA1 | |
| SCHEMBL25856205 | 0.85 | GBA1 (0.35) | CYP2D6GBA1 | |
| SCHEMBL25856389 | 0.85 | CYP1A2 (0.36) | CYP1A2CYP2D6ALOX15OPRM1OPRK1 | |
| SCHEMBL24480701 | 0.81 | GBA1 (0.40) | TRPV6GBA1 | |
| SCHEMBL17471124 | 0.77 | GNAO1 (0.41) | GBA1 | |
| SCHEMBL12109922 | 0.75 | KMT2A (0.36) | CYP2D6OPRM1OPRK1OPRL1TRPV6 | |
| SCHEMBL29317239 | 0.75 | ACHE (0.41) | GBA1 | |
| SCHEMBL25856382 | 0.75 | TACR1 (0.31) | — | |
| SCHEMBL24480306 | 0.74 | KMT2A (0.36) | CYP2D6OPRM1OPRK1OPRL1TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |