SCHEMBL25856434

SCHEMBL25856434

Cc1cc(/C=C/c2ccc(S)cc2)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.53
PTGS1 P23219 7/20 0.48
PTGS2 P35354 7/20 0.48
ALOX5 P09917 7/20 0.48
LCK P06239 2/20 0.48
NQO2 P16083 2/20 0.47
TUBB1 Q9H4B7 2/20 0.45
RELA Q04206 1/20 0.44
TTR P02766 1/20 0.44
TP53 P04637 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
PTPN2 P17706 1/20 0.43
PTPN1 P18031 1/20 0.43
PTPN6 P29350 1/20 0.43
NFE2L2 Q16236 1/20 0.42
RGS12 O14924 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1824384 0.88 LCK (0.61) BACE1PTGS1PTGS2ALOX5LCK
SCHEMBL1824386 0.88 LCK (0.61) BACE1PTGS1PTGS2ALOX5LCK
SCHEMBL1825879 0.84 BACE1 (0.70) BACE1PTGS1PTGS2ALOX5LCK
SCHEMBL1825877 0.84 BACE1 (0.70) BACE1PTGS1PTGS2ALOX5LCK
SCHEMBL172757 0.82 ALOX5 (0.66) BACE1PTGS1PTGS2ALOX5LCK
SCHEMBL1824536 0.80 PTGS1 (0.68) PTGS1PTGS2ALOX5LCKTTR
SCHEMBL1824535 0.80 PTGS1 (0.68) PTGS1PTGS2ALOX5LCKTTR
SCHEMBL24222559 0.78 TUBB1 (0.57) BACE1PTGS1PTGS2ALOX5LCK
SCHEMBL10054225 0.78 LCK (0.56) BACE1PTGS1PTGS2ALOX5LCK
SCHEMBL17356222 0.78 KDM4E (0.68) BACE1PTGS1PTGS2ALOX5LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023133875-A1 MULTIFUNCTIONAL GROUP METAL CORROSION INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 嘉庚创新实验室 2023-07-20 WO disclosed