Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703769 | 0.89 | ACHE (0.47) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL2842528 | 0.88 | ACHE (0.47) | ACHECHRM5ADRA2C | |
| SCHEMBL1286687 | 0.85 | ACHE (0.78) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL22703767 | 0.85 | ACHE (0.55) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL26461975 | 0.83 | ACHE (0.75) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL22703771 | 0.83 | ACHE (0.43) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL13874596 | 0.80 | ACHE (0.59) | ACHECHRM5ADRA2C | |
| SCHEMBL14454166 | 0.79 | THRB (0.42) | ACHECHRM5ADRA2CTHRBLMNA | |
| SCHEMBL24294614 | 0.79 | ACHE (0.41) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL724801 | 0.78 | ACHE (0.62) | ACHECHRM5ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |