SCHEMBL25857131

SCHEMBL25857131

C/C(=N\C(=O)NCCN1C(=O)C2C3C=CC(O3)C2C1=O)Nc1ncccn1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.43
OPRD1 P41143 1/20 0.43
OPRK1 P41145 1/20 0.43
ALDH1A1 P00352 13/20 0.41
HTT P42858 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
CYP3A4 P08684 1/20 0.34
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24746662 0.87 ALDH1A1 (0.41) OPRM1OPRD1OPRK1ALDH1A1HTT
SCHEMBL24746986 0.81 OPRM1 (0.38) OPRM1OPRD1OPRK1ALDH1A1HTT
SCHEMBL24746990 0.78 ALDH1A1 (0.39) OPRM1OPRD1OPRK1ALDH1A1HTT
SCHEMBL24746660 0.73 ALDH1A1 (0.51) OPRM1OPRD1OPRK1ALDH1A1HTT
SCHEMBL18641997 0.72 OPRM1 (0.50) OPRM1OPRD1OPRK1ALDH1A1TDP1
SCHEMBL22100058 0.70 OPRM1 (0.43) OPRM1OPRD1OPRK1ALDH1A1HTT
SCHEMBL24746658 0.70 ALDH1A1 (0.52) OPRM1OPRD1OPRK1ALDH1A1LMNA
SCHEMBL24746894 0.69 ALDH1A1 (0.51) OPRM1OPRD1OPRK1ALDH1A1HTT
SCHEMBL24747003 0.68 ALDH1A1 (0.43) OPRM1OPRD1OPRK1ALDH1A1NPC1
SCHEMBL22863834 0.68 OPRM1 (0.47) OPRM1OPRD1OPRK1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 OPRM1 2522/4885OPRD1 3897/4885OPRK1 3789/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 OPRM1 2522/4885OPRD1 3897/4885OPRK1 3789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.