Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793650 | 0.85 | IMPDH2 (0.41) | MAPTRAB9AIMPDH2CHUKMEN1 | |
| SCHEMBL31468033 | 0.85 | IMPDH2 (0.41) | MAPTRAB9AIMPDH2CHUKMEN1 | |
| SCHEMBL16274529 | 0.85 | POLB (0.41) | MAPTRAB9ACHUKMEN1KMT2A | |
| SCHEMBL30502565 | 0.76 | KDM4E (0.43) | IMPDH2GAAACHEPOLBL3MBTL1 | |
| SCHEMBL24575364 | 0.76 | IMPDH2 (0.43) | MAPTRAB9AIMPDH2CHUKGAA | |
| SCHEMBL30771962 | 0.76 | IMPDH2 (0.43) | MAPTRAB9AIMPDH2CHUKGAA | |
| SCHEMBL3393453 | 0.76 | ALDH1A1 (0.44) | MAPTRAB9AIMPDH2CHUKMEN1 | |
| SCHEMBL25857309 | 0.76 | FLT1 (0.43) | MAPTRAB9AIMPDH2CHUKMEN1 | |
| SCHEMBL30645164 | 0.74 | MEN1 (0.50) | MAPTRAB9AMEN1KMT2AGFER | |
| SCHEMBL2306302 | 0.74 | MEN1 (0.50) | MAPTRAB9AMEN1KMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |