Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | LATS1 | O95835 | 1/20 | 0.41 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SOD1 | P00441 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24379642 | 0.86 | GOT1 (0.41) | FLT1KDRMAPTRAB9AGOT1 | |
| SCHEMBL26667326 | 0.82 | GOT1 (0.62) | FLT1KDRMAPTRAB9AGOT1 | |
| SCHEMBL793650 | 0.80 | IMPDH2 (0.41) | FLT1KDRMAPTRAB9AGOT1 | |
| SCHEMBL31468033 | 0.80 | IMPDH2 (0.41) | FLT1KDRMAPTRAB9AGOT1 | |
| SCHEMBL25857264 | 0.79 | LATS1 (0.41) | FLT1KDRLATS1LATS2ALDH1A1 | |
| SCHEMBL18454567 | 0.77 | GOT1 (0.66) | MAPTRAB9AGOT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL26118128 | 0.76 | IL1B (0.37) | FLT1KDRMAPTRAB9ALATS1 | |
| SCHEMBL24574756 | 0.76 | IL1B (0.37) | FLT1KDRMAPTRAB9ALATS1 | |
| SCHEMBL24379632 | 0.76 | PRKCH (0.39) | FLT1KDRMAPTRAB9ALATS1 | |
| SCHEMBL25857239 | 0.76 | MAPT (0.35) | MAPTRAB9AGOT1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |