Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17071834 | 0.87 | ABCB11 (0.41) | ABCB11GABRA1GABRB1PSEN1PSEN2 | |
| SCHEMBL16770774 | 0.87 | ABCB11 (0.41) | ABCB11GABRA1GABRB1PSEN1PSEN2 | |
| SCHEMBL19430514 | 0.83 | NR3C1 (0.36) | GABRA1GABRB1RAPGEF4SCN4A | |
| SCHEMBL22169021 | 0.80 | PSEN1 (0.32) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13238643 | 0.79 | TSHR (0.37) | GABRA1GABRB1ADRB2RAPGEF4 | |
| SCHEMBL25852597 | 0.79 | SLC6A4 (0.33) | — | |
| SCHEMBL17025364 | 0.78 | GABRA1 (0.37) | GABRA1GABRB1RAPGEF4 | |
| SCHEMBL17025386 | 0.78 | GABRA1 (0.37) | GABRA1GABRB1RAPGEF4 | |
| SCHEMBL6124148 | 0.78 | GABRA1 (0.39) | GABRA1GABRB1ADRB2TRPA1RAPGEF4 | |
| SCHEMBL20738481 | 0.78 | ABCB11 (0.36) | ABCB11TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |