SCHEMBL25857261

SCHEMBL25857261

CCC(C)(C)N/C(N)=N/C(=O)Nc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.45
PKM P14618 1/20 0.44
NAMPT P43490 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MAPT P10636 4/20 0.39
GAA P10253 4/20 0.39
RAB9A P51151 2/20 0.39
HPGD P15428 1/20 0.39
CHIT1 Q13231 1/20 0.39
ADRA2A P08913 1/20 0.39
KDM4E B2RXH2 3/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HTR3E A5X5Y0 1/20 0.38
HTR3B O95264 1/20 0.38
HTR3A P46098 1/20 0.38
HTR3D Q70Z44 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24747001 0.85 KDM1A (0.46) KDM1AL3MBTL1MAPTGAARAB9A
SCHEMBL24746975 0.78 GRIN2D (0.55) KDM1AL3MBTL1NPSR1MAPTGAA
SCHEMBL10597468 0.77 EPHX1 (0.55) NAMPTL3MBTL1MAPTRAB9AKDM4E
SCHEMBL11668524 0.72 HDAC1 (0.51) KDM1AKDM4EHTR3EHTR3BHTR3A
SCHEMBL4475840 0.72 MAPT (0.51) KDM1AMAPTGAARAB9AKMT2A
SCHEMBL12251941 0.71 MAPT (0.49) NAMPTNPSR1MAPTGAARAB9A
SCHEMBL16139552 0.70 EPHX2 (0.54) KDM1AL3MBTL1NPSR1MAPTGAA
SCHEMBL19891235 0.70 ALDH1A1 (0.60) L3MBTL1MAPTGAARAB9AHPGD
SCHEMBL25857027 0.70 KDM1A (0.50) KDM1AMAPTGAAHPGDCHIT1
SCHEMBL18638471 0.70 PDK1 (0.56) L3MBTL1MAPTGAARAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 KDM1A 1558/4885PKM 2211/4885NAMPT 1780/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 KDM1A 1558/4885PKM 2211/4885NAMPT 1780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.