Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.41 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AOC1 | P19801 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690210 | 0.80 | EP300 (0.47) | KAT2BEP300KAT8KDM4EMAPKAPK2 | |
| SCHEMBL25857309 | 0.79 | FLT1 (0.43) | LATS1LATS2FLT1KDRKDM4E | |
| SCHEMBL11293218 | 0.72 | EP300 (0.40) | KAT2BEP300KAT8KDM4EMAPKAPK2 | |
| SCHEMBL31197276 | 0.72 | EP300 (0.40) | KAT2BEP300KAT8FLT1KDR | |
| SCHEMBL30994952 | 0.72 | AXL (0.40) | KAT2BEP300KAT8KDM4EMAPKAPK2 | |
| SCHEMBL25254434 | 0.72 | EP300 (0.40) | KAT2BEP300KAT8FLT1KDR | |
| SCHEMBL29276232 | 0.72 | AXL (0.40) | KAT2BEP300KAT8KDM4EMAPKAPK2 | |
| SCHEMBL25857289 | 0.69 | LATS1 (0.41) | LATS1LATS2KDRKDM4EALDH1A1 | |
| SCHEMBL24855963 | 0.68 | KDR (0.39) | LATS1LATS2KDRALDH1A1CYP1A2 | |
| SCHEMBL31197257 | 0.68 | PRKCZ (0.54) | CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |