Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.41 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GOT1 | P17174 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | ACOX1 | Q15067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27692880 | 0.77 | LATS1 (0.47) | LATS1LATS2CYP3A4MAOAALDH1A1 | |
| SCHEMBL14611339 | 0.77 | NPC1 (0.67) | NPC1RAB9ACYP3A4MAOAALDH1A1 | |
| SCHEMBL30913262 | 0.75 | LATS1 (0.38) | LATS1LATS2ALDH1A1MPOCLK4 | |
| SCHEMBL19153319 | 0.75 | MAOA (0.37) | NPC1RAB9ACYP3A4MAOAALDH1A1 | |
| SCHEMBL30502555 | 0.75 | MAOA (0.37) | NPC1RAB9ACYP3A4MAOAALDH1A1 | |
| SCHEMBL30913247 | 0.74 | TRPM8 (0.42) | LATS1LATS2NPC1RAB9AKDM4E | |
| SCHEMBL30913245 | 0.74 | LATS1 (0.38) | LATS1LATS2MAOA | |
| SCHEMBL30913253 | 0.73 | LATS1 (0.34) | LATS1LATS2NPC1ALDH1A1EGFR | |
| SCHEMBL13107488 | 0.73 | LATS1 (0.44) | LATS1LATS2CYP3A4MAOAALDH1A1 | |
| SCHEMBL2736702 | 0.72 | LATS1 (0.50) | LATS1LATS2CYP3A4LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |