Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25852035 | 0.82 | AOC3 (0.50) | AOC3TAAR1MAPTTP53ACHE | |
| SCHEMBL25833347 | 0.82 | AOC3 (0.47) | AOC3TAAR1GBA1SLC6A2SLC6A4 | |
| SCHEMBL25857409 | 0.80 | AOC3 (0.42) | AOC3TAAR1MAPTTP53ACHE | |
| SCHEMBL25853184 | 0.78 | AOC3 (0.41) | AOC3TAAR1MAPTTP53CCR5 | |
| SCHEMBL14569059 | 0.74 | ACHE (0.44) | AOC3TAAR1MAPTTP53ACHE | |
| SCHEMBL25853034 | 0.74 | AOC3 (0.43) | AOC3TAAR1MAPTTP53ACHE | |
| SCHEMBL257406 | 0.73 | ACHE (0.52) | AOC3TAAR1MAPTTP53ACHE | |
| SCHEMBL598866 | 0.72 | HDAC4 (0.55) | AOC3MAPTTP53ACHEACP3 | |
| Ammonia Solution, Strong SCHEMBL28824259 | 0.72 | ACHE (0.50) | AOC3TAAR1MAPTTP53ACHE | |
| SCHEMBL12329329 | 0.72 | ACHE (0.50) | AOC3TAAR1MAPTTP53ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |