Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857406 | 0.84 | AOC3 (0.43) | AOC3TAAR1ALDH1A1MAOBMAPT | |
| SCHEMBL25833396 | 0.84 | AOC3 (0.43) | AOC3TAAR1ALDH1A1MAOBMAPT | |
| SCHEMBL25857357 | 0.80 | AOC3 (0.45) | AOC3TAAR1TP53MAPTHTT | |
| SCHEMBL25852035 | 0.79 | AOC3 (0.50) | AOC3TAAR1TP53MAPTGLA | |
| SCHEMBL25853184 | 0.75 | AOC3 (0.41) | AOC3TAAR1TP53MAPTCCR5 | |
| SCHEMBL25853034 | 0.71 | AOC3 (0.43) | AOC3TAAR1TP53MAPTACHE | |
| SCHEMBL598866 | 0.69 | HDAC4 (0.55) | AOC3ALDH1A1GAATP53MAPT | |
| SCHEMBL25262039 | 0.69 | AOC3 (0.43) | AOC3TAAR1ALDH1A1MAPTCTSB | |
| SCHEMBL11077019 | 0.68 | ALDH1A1 (0.42) | AOC3TAAR1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL14791097 | 0.68 | AOC3 (0.40) | AOC3TAAR1ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |