SCHEMBL25857602 — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	AMY1A	P0DUB6	1/20	0.39

▸	MGAM	O43451	2/20	0.38

▸	GAA	P10253	2/20	0.38

▸	SI	P14410	2/20	0.38

▸	MGAM2	Q2M2H8	2/20	0.38

▸	SCN9A	Q15858	6/20	0.35

▸	FYN	P06241	2/20	0.35

▸	UGCG	Q16739	1/20	0.35

▸	PDE7A	Q13946	1/20	0.34

▸	KDM4E	B2RXH2	2/20	0.33

▸	LMNA	P02545	2/20	0.33

▸	HTT	P42858	2/20	0.33

▸	KMT2A	Q03164	2/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	ALOX12	P18054	1/20	0.33

▸	LRRK2	Q5S007	1/20	0.33

▸	PGR	P06401	1/20	0.33

▸	NR3C2	P08235	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25296592	0.87	AMY1A (0.40)	AMY1AMGAMGAASIMGAM2
SCHEMBL25257750	0.85	AMY1A (0.39)	AMY1AMGAMGAASIMGAM2
SCHEMBL25258989	0.85	AMY1A (0.39)	AMY1AMGAMGAASIMGAM2
SCHEMBL25857608	0.81	SCN9A (0.33)	SCN9AFYNUGCGPDE7AKDM4E
SCHEMBL25857617	0.78	SCN9A (0.32)	SCN9AFYNUGCGPDE7AKDM4E
SCHEMBL26517604	0.75	UGCG (0.39)	SCN9AFYNUGCG
SCHEMBL31197243	0.72	CHEK1 (0.47)	—
SCHEMBL30108829	0.71	THRB (0.38)	AMY1AMGAMGAASIMGAM2
SCHEMBL28934467	0.71	PRNP (0.38)	MGAMGAASIMGAM2KMT2A
SCHEMBL28934693	0.71	KDM4E (0.38)	SCN9AUGCGKDM4ELMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023131277-A1	NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF	药捷安康(南京)科技股份有限公司	2023-07-13	—	—	WO	disclosed