Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.39 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24855740 | 0.82 | EP300 (0.40) | GPBAR1FYN | |
| SCHEMBL31673746 | 0.81 | MAOA (0.37) | SCN9AFYN | |
| SCHEMBL27355385 | 0.77 | SCN9A (0.44) | SCN9A | |
| SCHEMBL24855382 | 0.76 | EP300 (0.40) | GPBAR1 | |
| SCHEMBL26516215 | 0.75 | MGAT2 (0.41) | CDK2GSK3B | |
| SCHEMBL25857602 | 0.75 | AMY1A (0.39) | UGCGSCN9AFYN | |
| SCHEMBL26517619 | 0.73 | CLK1 (0.37) | GSK3B | |
| SCHEMBL31359797 | 0.72 | CDK9 (0.38) | CDK2GSK3BKCNH2 | |
| SCHEMBL24379596 | 0.72 | SCN9A (0.40) | SCN9A | |
| SCHEMBL25857608 | 0.71 | SCN9A (0.33) | UGCGSCN9AFYNGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023194964-A1 | FUSED PYRIDAZINE DERIVATIVES AS NLRP3 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-12 | — | — | WO | disclosed |