Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 9/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.31 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258554 | 0.86 | TSHR (0.41) | TSHRENPP2LPAR3LPAR1SMN1; SMN2 | |
| SCHEMBL3914438 | 0.85 | TSHR (0.55) | TSHRALDH1A1 | |
| SCHEMBL28061998 | 0.82 | TSHR (0.52) | TSHRALDH1A1 | |
| SCHEMBL7759192 | 0.82 | TSHR (0.52) | TSHRALDH1A1 | |
| SCHEMBL13109375 | 0.81 | TSHR (0.45) | TSHRENPP2LPAR3LPAR1TRPV1 | |
| SCHEMBL258599 | 0.80 | ALDH1A1 (0.44) | TSHRLPAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7760377 | 0.80 | TSHR (0.57) | TSHRALDH1A1 | |
| SCHEMBL195298 | 0.79 | TSHR (0.49) | TSHRALDH1A1 | |
| SCHEMBL258576 | 0.77 | THRB (0.47) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4067170 | 0.77 | TSHR (0.53) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063123-B2 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-22 | — | — | US | disclosed |
| US-8063123-B2 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-22 | — | — | US | disclosed |
| US-20070225414-A1 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT INTERNATIONAL LTD | 2007-09-27 | — | — | US | disclosed |
| US-20070225414-A1 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT INTERNATIONAL LTD | 2007-09-27 | — | — | US | disclosed |