Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6485409 | 0.81 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL6477252 | 0.79 | METAP2 (0.66) | METAP2METAP1 | |
| SCHEMBL6563460 | 0.79 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL6477441 | 0.79 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL6477893 | 0.76 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL6478013 | 0.75 | METAP2 (0.53) | METAP2METAP1 | |
| SCHEMBL6489481 | 0.74 | METAP2 (0.50) | METAP2METAP1 | |
| SCHEMBL6477096 | 0.74 | METAP2 (0.52) | METAP2METAP1 | |
| SCHEMBL6476471 | 0.74 | METAP2 (0.49) | METAP2METAP1 | |
| SCHEMBL6478153 | 0.68 | METAP2 (0.51) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230225996-A1 | BIOMARKERS OF METAP2 INHIBITORS AND APPLICATIONS THEREOF | SYNDEVRX, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225996-A1 | BIOMARKERS OF METAP2 INHIBITORS AND APPLICATIONS THEREOF | METAP2, METAP1, PEBP1 | METAP2 1/4885METAP1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.