Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 17/20 | 0.47 |
| ▸ | METAP1 | P53582 | 15/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6477441 | 1.00 | METAP2 (0.47) | METAP2METAP1GLSACACB | |
| SCHEMBL6477252 | 0.80 | METAP2 (0.66) | METAP2METAP1 | |
| SCHEMBL6477893 | 0.80 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL6485409 | 0.80 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL25857844 | 0.79 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL6939437 | 0.77 | METAP2 (0.40) | METAP2METAP1 | |
| SCHEMBL6478013 | 0.73 | METAP2 (0.53) | METAP2METAP1 | |
| SCHEMBL6489481 | 0.73 | METAP2 (0.50) | METAP2METAP1 | |
| SCHEMBL6476604 | 0.73 | METAP2 (0.50) | METAP2METAP1 | |
| SCHEMBL6477096 | 0.72 | METAP2 (0.52) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-B1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LAB (US) | 2004-10-27 | — | — | EP | claimed |