Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | GAK | O14976 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25858155 | 0.87 | NSD2 (0.39) | ATMNSD2CASP6G6PDMAOA | |
| SCHEMBL30108705 | 0.83 | KMT2A (0.47) | ATMNSD2CASP6G6PDMEN1 | |
| SCHEMBL30108769 | 0.82 | NSD2 (0.43) | ATMNSD2CASP6G6PDMEN1 | |
| SCHEMBL25253888 | 0.80 | ALDH1A1 (0.44) | ATMMAPTKDM4EHTTSMN1; SMN2 | |
| SCHEMBL25856341 | 0.74 | HSP90AA1 (0.38) | MAOAMAOBMEN1KMT2AHSP90AA1 | |
| SCHEMBL30488502 | 0.74 | KDM4E (0.38) | MAOAMAOBMEN1KMT2AHSP90AA1 | |
| SCHEMBL25299180 | 0.74 | KDM4E (0.38) | MAOAMAOBMEN1KMT2AHSP90AA1 | |
| SCHEMBL30108755 | 0.74 | KMT2A (0.47) | ATMNSD2CASP6G6PDMEN1 | |
| SCHEMBL25858077 | 0.74 | KDM4E (0.35) | MAOAMAOBKMT2AMAPTKDM4E | |
| SCHEMBL30108834 | 0.69 | G6PD (0.44) | ATMNSD2CASP6G6PDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |