Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25858132 | 0.87 | ATM (0.37) | NSD2CASP6G6PDMAOAMAOB | |
| SCHEMBL30108705 | 0.72 | KMT2A (0.47) | NSD2CASP6G6PDPDE4DATM | |
| SCHEMBL30108834 | 0.72 | G6PD (0.44) | NSD2CASP6G6PDATMDYRK1A | |
| SCHEMBL25299180 | 0.70 | KDM4E (0.38) | MAOAMAOBPDE4DMAPTCCR1 | |
| SCHEMBL25856341 | 0.70 | HSP90AA1 (0.38) | MAOAMAOBPDE4DPDE3AEGFR | |
| SCHEMBL30488502 | 0.70 | KDM4E (0.38) | MAOAMAOBPDE4DMAPTCCR1 | |
| SCHEMBL25858077 | 0.70 | KDM4E (0.35) | MAOAMAOBPDE4DMAPTKDM4E | |
| SCHEMBL30108680 | 0.69 | NSD2 (0.43) | NSD2CASP6G6PDATMEGFR | |
| SCHEMBL30108769 | 0.69 | NSD2 (0.43) | NSD2CASP6G6PDPDE2APDE4D | |
| SCHEMBL30108849 | 0.68 | G6PD (0.44) | NSD2CASP6G6PDATMDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |