Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108834 | 0.86 | G6PD (0.44) | NSD2CASP6G6PDGLO1KDM4E | |
| SCHEMBL30108769 | 0.85 | NSD2 (0.43) | NSD2CASP6G6PDKDM4EMAPT | |
| SCHEMBL30108829 | 0.83 | THRB (0.38) | MAPTMEN1KMT2ATHRB | |
| SCHEMBL28934827 | 0.82 | KDM4E (0.41) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL30108726 | 0.82 | KDM4E (0.41) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL30108849 | 0.77 | G6PD (0.44) | NSD2CASP6G6PDGLO1KDM4E | |
| SCHEMBL30108774 | 0.77 | MAOA (0.36) | MC4RTHRB | |
| SCHEMBL30108691 | 0.75 | THRB (0.34) | KDM4EMAPTATMMEN1KMT2A | |
| SCHEMBL25257750 | 0.74 | AMY1A (0.39) | KDM4EMAPTATMMEN1KMT2A | |
| SCHEMBL28934467 | 0.73 | PRNP (0.38) | MAPTMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |