Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 12/20 | 0.40 |
| ▸ | BRAF | P15056 | 6/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | WRN | Q14191 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | BLK | P51451 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20481475 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TSHRARCDK8KDR | |
| SCHEMBL18038027 | 0.88 | AR (0.44) | ALDH1A1TSHRARCDK8KDR | |
| SCHEMBL18038068 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRARCDK8KDR | |
| SCHEMBL25858664 | 0.87 | KMT2A (0.47) | ALDH1A1TSHR | |
| SCHEMBL23258948 | 0.86 | DNM2 (0.44) | ALDH1A1TSHRARCDK8KDR | |
| SCHEMBL23258959 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TSHRARCDK8KDR | |
| SCHEMBL23258366 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRARCDK8KDR | |
| SCHEMBL23259063 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRARCDK8KDR | |
| SCHEMBL18037978 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRARCDK8KDR | |
| SCHEMBL23258604 | 0.85 | STK17A (0.52) | ALDH1A1TSHRARCDK8KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271926-A1 | INHIBITION OF OLIG2 ACTIVITY | Curtana Pharmaceuticals, Inc. | 2023-08-31 | — | — | US | disclosed |
| US-11691951-B2 | Inhibition of Olig2 activity | Curtana Pharmaceuticals, Inc. (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691951-B2 | Inhibition of Olig2 activity | GLI2, ING2, GMFG | ALDH1A1 1478/4885TSHR 4810/4885AR 3964/4885 |
| US-20230271926-A1 | INHIBITION OF OLIG2 ACTIVITY | GLI2, ING2, GMFG | ALDH1A1 1478/4885TSHR 4810/4885AR 3964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.