Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
| ▸ | MYH9 | P35579 | 1/20 | 0.67 |
| ▸ | MYH10 | P35580 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
| ▸ | HBB | P68871 | 1/20 | 0.67 |
| ▸ | MYH2 | Q9UKX2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25859658 | 0.85 | MEN1 (0.64) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23235464 | 0.83 | MEN1 (0.67) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23235460 | 0.83 | MEN1 (0.67) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23235540 | 0.83 | MEN1 (0.76) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23235542 | 0.83 | MEN1 (0.76) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL19200636 | 0.81 | MEN1 (0.81) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL19183407 | 0.81 | MEN1 (0.81) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL31218583 | 0.81 | MEN1 (0.81) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL22512479 | 0.81 | MEN1 (0.81) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23235584 | 0.81 | MEN1 (0.85) | MEN1KMT2ACYP3A4MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227452-A1 | NONMUSCLE MYOSIN II INHIBITORS | THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227452-A1 | NONMUSCLE MYOSIN II INHIBITORS | MYH2, MYO3B, MYO1B | MEN1 1652/4885KMT2A 3765/4885CYP3A4 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.