Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585920 | 0.91 | XPO1 (0.39) | XPO1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2346553 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL2346544 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL28674985 | 0.82 | HSD17B10 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL2584512 | 0.82 | TRPM8 (0.46) | LMNAALDH1A1TDP1 | |
| SCHEMBL28674986 | 0.82 | HSD17B10 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL2586557 | 0.82 | TRPM8 (0.46) | XPO1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2584740 | 0.81 | LMNA (0.53) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22040222 | 0.81 | NR3C2 (0.43) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL3625341 | 0.81 | LMNA (0.53) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |