Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010994 | 0.85 | DRD2 (0.59) | DRD2DRD4ESR2MAOBMAOA | |
| SCHEMBL18388811 | 0.71 | HDAC1 (0.33) | HDAC1 | |
| SCHEMBL4594991 | 0.70 | MAPT (0.40) | HDAC1KDM4EMEN1NPC1MAPT | |
| SCHEMBL30952883 | 0.70 | HTR5A (0.37) | HDAC1KDM4EMEN1NPC1MAPT | |
| SCHEMBL8348811 | 0.70 | MAPT (0.44) | HDAC1KDM4EMEN1NPC1MAPT | |
| SCHEMBL24731749 | 0.70 | CHEK1 (0.44) | DRD4HDAC1 | |
| SCHEMBL7647136 | 0.67 | PDE3B (0.49) | MAOBMAOAKDM4EMEN1NPC1 | |
| SCHEMBL30549 | 0.66 | — | — | |
| SCHEMBL33917 | 0.65 | DRD2 (0.70) | DRD2DRD4HDAC1ESR2 | |
| SCHEMBL10848263 | 0.65 | DRD2 (0.44) | DRD2DRD4ESR2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865477-B1 | CARBENE COMPOUND, CARBENE-METAL NANOPARTICLE COMPLEX AND PREPARATION METHOD THEREOF | KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR) | 2023-07-12 | — | — | EP | disclosed |