Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | INSR | P06213 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13115655 | 0.82 | FGFR1 (0.71) | FGFR1MAPK1FGFR2FGFR3DYRK1A | |
| SCHEMBL20060303 | 0.77 | KDM4E (0.59) | FGFR1FGFR2FGFR3DYRK1ACHEK1 | |
| SCHEMBL12354 | 0.77 | KDM4E (0.59) | FGFR1FGFR2FGFR3DYRK1ACHEK1 | |
| SCHEMBL28201501 | 0.77 | DYRK1A (0.53) | FGFR1MAPK1DYRK1APLK4CHEK1 | |
| SCHEMBL20386108 | 0.77 | FGFR1 (0.52) | KDM1AFGFR1MAPK1FGFR2FGFR3 | |
| SCHEMBL6837194 | 0.77 | KDM1A (0.70) | KDM1AFGFR1MAPK1FGFR2FGFR3 | |
| SCHEMBL20929593 | 0.76 | CCR1 (0.56) | KDM1ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL1318366 | 0.75 | FGFR1 (0.55) | KDM1AFGFR1MAPK1FGFR2FGFR3 | |
| SCHEMBL8264120 | 0.74 | FGFR1 (0.70) | FGFR1MAPK1FGFR2FGFR3DYRK1A | |
| SCHEMBL28200925 | 0.74 | FGFR1 (0.54) | KDM1AFGFR1MAPK1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023140640-A1 | HETEROARYL DERIVATIVE AND USES THEREOF | 한양대학교 산학협력단 | 2023-07-27 | — | — | WO | disclosed |