Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258535 | 0.96 | THRB (0.49) | THRBTSHRALDH1A1DGKAPOLB | |
| SCHEMBL13109397 | 0.90 | TSHR (0.53) | THRBTSHRALDH1A1DGKAPOLB | |
| SCHEMBL258496 | 0.90 | TSHR (0.49) | THRBTSHRALDH1A1DGKAPOLB | |
| SCHEMBL258498 | 0.85 | THRB (0.51) | THRBTSHRALDH1A1DGKAPOLB | |
| SCHEMBL28959481 | 0.81 | THRB (0.66) | THRBTSHRALDH1A1DGKAPOLB | |
| SCHEMBL258576 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1DGKAPOLB | |
| SCHEMBL8492855 | 0.80 | THRB (0.65) | THRBTSHRALDH1A1DGKAPOLB | |
| SCHEMBL5072271 | 0.80 | THRB (0.63) | THRBTSHRALDH1A1DGKAPOLB | |
| Phosphoric Acid SCHEMBL867302 | 0.79 | THRB (0.68) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13109377 | 0.79 | LPAR1 (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063123-B2 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-22 | — | — | US | disclosed |
| US-20070225414-A1 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT INTERNATIONAL LTD | 2007-09-27 | — | — | US | disclosed |
| US-20070225414-A1 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT INTERNATIONAL LTD | 2007-09-27 | — | — | US | disclosed |