Eptazocine

Eptazocine

SCHEMBL25862

CN1CC[C@]2(C)C[C@@H](Cc3ccc(O)cc32)C1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.51
OPRM1 P35372 8/20 0.48
OPRK1 P41145 7/20 0.48
OPRD1 P41143 8/20 0.47
SIGMAR1 Q99720 5/20 0.46
MRGPRX2 Q96LB1 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eptazocine SCHEMBL29388574 1.00 HSD11B1 (0.51) HSD11B1OPRM1OPRK1OPRD1SIGMAR1
Eptazocine SCHEMBL1650016 1.00 HSD11B1 (0.51) HSD11B1OPRM1OPRK1OPRD1SIGMAR1
Eptazocine SCHEMBL9487496 0.99 HSD11B1 (0.50) HSD11B1OPRM1OPRK1OPRD1SIGMAR1
Eptazocine SCHEMBL30901223 0.99 HSD11B1 (0.50) HSD11B1OPRM1OPRK1OPRD1SIGMAR1
Eptazocine SCHEMBL395495 0.99 HSD11B1 (0.50) HSD11B1OPRM1OPRK1OPRD1SIGMAR1
SCHEMBL11651818 0.82 SIGMAR1 (0.44) OPRK1OPRD1SIGMAR1
SCHEMBL9488119 0.82 HSD11B1 (0.52) HSD11B1OPRM1OPRK1SIGMAR1MRGPRX2
SCHEMBL30945838 0.82 SIGMAR1 (0.41) HSD11B1OPRM1OPRK1OPRD1SIGMAR1
SCHEMBL20394548 0.82 HSD11B1 (0.52) HSD11B1OPRM1OPRK1SIGMAR1MRGPRX2
Bromide SCHEMBL11653724 0.81 OPRM1 (0.50) HSD11B1OPRM1OPRK1OPRD1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7680 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
US-20250228771-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-07-17 US claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP claimed
EP-4565202-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-06-11 EP claimed
WO-2025080559-A1 METHODS AND COMPOSITIONS FOR TREATING DRUG OVERDOSE ENALARE THERAPEUTICS INC. (US) 2025-04-17 WO claimed
US-20250114370-A1 METHODS AND COMPOSITIONS FOR TREATING DRUG OVERDOSE ENALARE THERAPEUTICS INC (US) 2025-04-10 US claimed
US-20250017846-A1 TOPICAL ANALGESICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-01-16 US claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 WO claimed
EP-0848960-A2 Adhesive for dermal or transdermal therapy systems RÖHM GMBH (DE) 1998-06-24 EP claimed
EP-0848950-A2 Adhesive and binder compositions based on a (meth)acrylate polymer, an organic acid and a plasticiser RÖHM GMBH (DE) 1998-06-24 EP claimed
WO-1997033566-A2 COMPOSITION AND DOSAGE FORM COMPRISING OPIOID ANTAGONIST ALZA CORPORATION (US) 1997-09-18 WO claimed
EP-0785775-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS Euroceltique S.A. (LU) 1997-07-30 EP claimed
EP-0731694-A4 1996-10-02 EP claimed
EP-0731694-A1 OPIOID FORMULATIONS FOR TREATING PAIN Euroceltique S.A. (LU) 1996-09-18 EP claimed
CN-1130352-A Method for relieving pain by orally administering 24-hour sustained-release opioid dosage form capable of rapidly increasing initial blood concentration of patient EURO CELTIQUE SA (LU) 1996-09-04 CN claimed
WO-1996014058-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO-CELTIQUE, S.A. (LU) 1996-05-17 WO claimed
WO-1995014460-A1 OPIOID FORMULATIONS FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 1995-06-01 WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 EP claimed