Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25854482 | 0.94 | MMP3 (0.34) | MMP3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25863216 | 0.86 | NPC1 (0.41) | MMP3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25863220 | 0.85 | HDAC2 (0.39) | MMP3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19375644 | 0.81 | MMP3 (0.35) | MMP3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25863476 | 0.80 | PSMB5 (0.44) | RENSIRT2SIRT1SIRT5 | |
| SCHEMBL25854480 | 0.80 | HDAC2 (0.39) | MMP3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25854483 | 0.80 | NPC1 (0.41) | MMP3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17302707 | 0.78 | LTA4H (0.44) | MMP3NPC1RAB9ASMN1; SMN2KDM1A | |
| SCHEMBL24479489 | 0.76 | RAB9A (0.41) | MMP3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22459909 | 0.75 | MMP3 (0.35) | MMP3HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696956-B2 | Bicyclic peptide ligands specific for EphA2 | BICYCLETX LIMITED (GB) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696956-B2 | Bicyclic peptide ligands specific for EphA2 | EPHA2, EPHB2, ERBB2 | MMP3 4313/4885HDAC3 4811/4885HDAC4 4816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.