Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21097238 | 0.90 | SIRT5 (0.49) | SIRT5PSMB5PSMB2SIRT1SIRT2 | |
| SCHEMBL25863476 | 0.90 | PSMB5 (0.44) | SIRT5PSMB5PSMB2PSMB1SIRT1 | |
| SCHEMBL21097237 | 0.89 | PSMB8 (0.49) | SIRT5PSMB5SIRT1SIRT2PSMB8 | |
| SCHEMBL18774075 | 0.87 | SIRT2 (0.50) | SIRT5PSMB5SIRT1SIRT2PSMB8 | |
| SCHEMBL18752309 | 0.87 | SIRT2 (0.49) | SIRT5PSMB5SIRT1SIRT2PSMB8 | |
| SCHEMBL17039855 | 0.82 | SIRT5 (0.57) | SIRT5PSMB5SIRT1SIRT2PSMB8 | |
| SCHEMBL17750718 | 0.82 | SIRT5 (0.57) | SIRT5PSMB5SIRT1SIRT2PSMB8 | |
| SCHEMBL21097236 | 0.81 | SIRT1 (0.40) | SIRT5PSMB5PSMB2PSMB1SIRT1 | |
| SCHEMBL17750717 | 0.81 | SIRT5 (0.56) | SIRT5PSMB5SIRT1SIRT2PSMB8 | |
| SCHEMBL17039859 | 0.81 | SIRT5 (0.56) | SIRT5PSMB5SIRT1SIRT2PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696956-B2 | Bicyclic peptide ligands specific for EphA2 | BICYCLETX LIMITED (GB) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696956-B2 | Bicyclic peptide ligands specific for EphA2 | EPHA2, EPHB2, ERBB2 | SIRT5 4536/4885PSMB5 3617/4885PSMB2 3834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.