Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.79 |
| ▸ | LMNA | P02545 | 5/20 | 0.79 |
| ▸ | AR | P10275 | 5/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.79 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.79 |
| ▸ | ESR1 | P03372 | 4/20 | 0.79 |
| ▸ | SHBG | P04278 | 4/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11868140 | 1.00 | PGR (0.79) | PGRLMNAARCYP3A4SLC6A4 | |
| SCHEMBL25863862 | 1.00 | PGR (0.79) | PGRLMNAARCYP3A4SLC6A4 | |
| SCHEMBL11859369 | 0.92 | PGR (0.67) | PGRLMNAARCYP3A4SLC6A4 | |
| SCHEMBL11858281 | 0.91 | PGR (0.78) | PGRLMNAARCYP3A4SLC6A4 | |
| SCHEMBL10930932 | 0.91 | PGR (0.78) | PGRLMNAARCYP3A4SLC6A4 | |
| SCHEMBL10929203 | 0.91 | PGR (0.78) | PGRLMNAARCYP3A4SLC6A4 | |
| SCHEMBL1843682 | 0.91 | PGR (0.78) | PGRLMNAARCYP3A4SLC6A4 | |
| Norgestrel SCHEMBL4319113 | 0.88 | PGR (1.00) | PGRLMNAARCYP3A4SLC6A4 | |
| Levonorgestrel SCHEMBL21741985 | 0.88 | PGR (1.00) | PGRLMNAARCYP3A4SLC6A4 | |
| Levonorgestrel SCHEMBL691861 | 0.88 | PGR (1.00) | PGRLMNAARCYP3A4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227492-A1 | MONOMERIC AND OLIGOMERIC COMPOUND EMBODIMENTS AS CONTRACEPTIVES AND THERAPIES AND METHODS OF MAKING AND USING THE SAME | THE USA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227492-A1 | MONOMERIC AND OLIGOMERIC COMPOUND EMBODIMENTS AS CONTRACEPTIVES AND THERAPIES AND METHODS OF MAKING AND USING THE SAME | SHBG, CYP19A1, GNRHR | PGR 16/4885LMNA 388/4885AR 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.