Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 10/20 | 0.39 |
| ▸ | JAK2 | O60674 | 9/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28934535 | 0.91 | NLRP3 (0.51) | NLRP3ALDH1A1IL1BJAK3JAK2 | |
| SCHEMBL28934539 | 0.91 | NLRP3 (0.51) | NLRP3ALDH1A1IL1BJAK3JAK2 | |
| SCHEMBL25864163 | 0.91 | NLRP3 (0.45) | NLRP3ALDH1A1IL1B | |
| SCHEMBL30108776 | 0.91 | NLRP3 (0.51) | NLRP3ALDH1A1IL1BJAK3JAK2 | |
| SCHEMBL25854968 | 0.87 | NLRP3 (0.47) | NLRP3ALDH1A1IL1B | |
| SCHEMBL25256054 | 0.87 | NLRP3 (0.62) | NLRP3IL1B | |
| SCHEMBL25297240 | 0.87 | NLRP3 (0.62) | NLRP3IL1B | |
| SCHEMBL30488518 | 0.87 | NLRP3 (0.62) | NLRP3IL1B | |
| SCHEMBL25864237 | 0.86 | NLRP3 (0.51) | NLRP3IL1BJAK3JAK2JAK1 | |
| SCHEMBL30488483 | 0.86 | NLRP3 (0.46) | NLRP3ALDH1A1IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |