Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNMT | P50135 | 1/20 | 0.75 |
| ▸ | NNMT | P40261 | 3/20 | 0.67 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.67 |
| ▸ | NSD2 | O96028 | 2/20 | 0.67 |
| ▸ | PCMT1 | P22061 | 2/20 | 0.67 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.67 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.67 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.67 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.67 |
| ▸ | RNMT | O43148 | 1/20 | 0.67 |
| ▸ | INMT | O95050 | 1/20 | 0.67 |
| ▸ | TPMT | P51580 | 1/20 | 0.67 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.67 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.67 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.67 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.67 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.67 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.67 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.67 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27092934 | 0.87 | HNMT (0.73) | HNMTNNMTPRMT5NSD2PCMT1 | |
| SCHEMBL27092929 | 0.87 | HNMT (0.73) | HNMTNNMTPRMT5NSD2PCMT1 | |
| SCHEMBL27092971 | 0.86 | HNMT (1.00) | HNMTNNMTPRMT5NSD2PCMT1 | |
| SCHEMBL27092976 | 0.86 | HNMT (1.00) | HNMTNNMTPRMT5NSD2PCMT1 | |
| SCHEMBL25864251 | 0.85 | DOT1L (0.64) | HNMTNNMTPRMT5NSD2PCMT1 | |
| Sinefungin SCHEMBL24478706 | 0.80 | NSD2 (1.00) | HNMTNNMTPRMT5NSD2PCMT1 | |
| Sinefungin SCHEMBL10400321 | 0.80 | NSD2 (1.00) | HNMTNNMTPRMT5NSD2PCMT1 | |
| Sinefungin SCHEMBL38665462 | 0.80 | NSD2 (1.00) | HNMTNNMTPRMT5NSD2PCMT1 | |
| Sinefungin SCHEMBL167609 | 0.80 | NSD2 (1.00) | HNMTNNMTPRMT5NSD2PCMT1 | |
| Sinefungin SCHEMBL20992057 | 0.80 | NSD2 (1.00) | HNMTNNMTPRMT5NSD2PCMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233592-A1 | PHARMACEUTICAL COMPOSITION FOR THE CHEMICAL INHIBITION OF TGS1 IN THE THERAPEUTIC TREATMENT OF TELOMEROPATHIES | UNIVERSITÀ DEGLI STUDI DI ROMA "LA SAPIENZA" (IT) | 2023-07-27 | — | — | US | disclosed |
| US-20230233592-A1 | PHARMACEUTICAL COMPOSITION FOR THE CHEMICAL INHIBITION OF TGS1 IN THE THERAPEUTIC TREATMENT OF TELOMEROPATHIES | UNIVERSITÀ DEGLI STUDI DI ROMA "LA SAPIENZA" (IT) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233592-A1 | PHARMACEUTICAL COMPOSITION FOR THE CHEMICAL INHIBITION OF TGS1 IN THE THERAPEUTIC TREATMENT OF TELOMEROPATHIES | POT1, SPTLC1, GAR1 | HNMT 2716/4885NNMT 2881/4885PRMT5 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.