Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNMT | P50135 | 2/20 | 1.00 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.67 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.67 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.67 |
| ▸ | NSD2 | O96028 | 3/20 | 0.67 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.67 |
| ▸ | NNMT | P40261 | 3/20 | 0.67 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.67 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.67 |
| ▸ | INMT | O95050 | 2/20 | 0.67 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.67 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.67 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.67 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.67 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.67 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.67 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.67 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.67 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.67 |
| ▸ | PNMT | P11086 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27092976 | 1.00 | HNMT (1.00) | HNMTDOT1LCARM1EHMT2NSD2 | |
| SCHEMBL25864245 | 0.86 | HNMT (0.75) | HNMTDOT1LCARM1EHMT2NSD2 | |
| SCHEMBL27092929 | 0.84 | HNMT (0.73) | HNMTDOT1LCARM1EHMT2NSD2 | |
| SCHEMBL27092934 | 0.84 | HNMT (0.73) | HNMTDOT1LCARM1EHMT2NSD2 | |
| SCHEMBL23815575 | 0.83 | HNMT (0.71) | HNMTDOT1LCARM1EHMT2NSD2 | |
| S-Adenosylhomocysteine SCHEMBL18826562 | 0.80 | DOT1L (1.00) | HNMTDOT1LCARM1EHMT2NSD2 | |
| S-Adenosylhomocysteine SCHEMBL13033864 | 0.80 | DOT1L (1.00) | HNMTDOT1LCARM1EHMT2NSD2 | |
| S-Adenosylhomocysteine SCHEMBL17316165 | 0.80 | DOT1L (1.00) | HNMTDOT1LCARM1EHMT2NSD2 | |
| S-Adenosylhomocysteine SCHEMBL21160481 | 0.80 | DOT1L (1.00) | HNMTDOT1LCARM1EHMT2NSD2 | |
| S-Adenosylhomocysteine SCHEMBL10871157 | 0.80 | DOT1L (1.00) | HNMTDOT1LCARM1EHMT2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4324928-A1 | SYNTHETIC REAGENTS FOR ENZYME-CATALYSED ALKYLATION | Universität Basel (CH) | 2024-02-21 | — | — | EP | claimed |
| EP-4324928-A1 | SYNTHETIC REAGENTS FOR ENZYME-CATALYSED ALKYLATION | Universität Basel (CH) | 2024-02-21 | — | — | EP | disclosed |