Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25855974 | 0.90 | NLRP3 (0.46) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25863870 | 0.89 | NLRP3 (0.34) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25864427 | 0.87 | KDM4E (0.32) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25864431 | 0.85 | NLRP3 (0.54) | NLRP3KDM4EALDH1A1GAA | |
| SCHEMBL25864507 | 0.82 | NLRP3 (0.41) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25296232 | 0.79 | NLRP3 (0.43) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25854744 | 0.79 | NLRP3 (0.43) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL30488486 | 0.79 | NLRP3 (0.43) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25864505 | 0.77 | NLRP3 (0.37) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25855972 | 0.77 | NLRP3 (0.41) | NLRP3KDM4EHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |