Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | IL1B | P01584 | 2/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25864504 | 0.89 | NLRP3 (0.35) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25856084 | 0.88 | NLRP3 (0.48) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25864507 | 0.88 | NLRP3 (0.41) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25864503 | 0.85 | ALDH1A1 (0.39) | KDM4EHSD17B10ALDH1A1LMNAGAA | |
| SCHEMBL25864067 | 0.84 | NLRP3 (0.54) | NLRP3IL1BTNF | |
| SCHEMBL25864513 | 0.82 | NLRP3 (0.43) | NLRP3IL1BTNF | |
| SCHEMBL25864241 | 0.81 | KDM4E (0.34) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25864303 | 0.81 | KDM4E (0.36) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25864312 | 0.80 | NLRP3 (0.44) | NLRP3KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL25863763 | 0.80 | NLRP3 (0.44) | NLRP3IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |