Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IL1B | P01584 | 7/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24695709 | 0.82 | IL1B (0.51) | IL1BTNFNLRP3 | |
| SCHEMBL30374762 | 0.72 | IL1B (0.38) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL26092175 | 0.72 | CRHR1 (0.31) | — | |
| SCHEMBL31200660 | 0.71 | IL1B (0.47) | IL1BTNFNLRP3MEN1KMT2A | |
| SCHEMBL26434220 | 0.70 | IL1B (0.42) | IL1BTNFNLRP3 | |
| SCHEMBL29455292 | 0.70 | SELL (0.55) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL851649 | 0.70 | SELL (0.55) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL22670876 | 0.69 | IL1B (0.45) | LMNAIL1BTNFNLRP3MEN1 | |
| SCHEMBL31200596 | 0.69 | IL1B (0.45) | LMNAIL1BTNFNLRP3MEN1 | |
| SCHEMBL26434223 | 0.69 | IL1B (0.52) | IL1BTNFNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |