SCHEMBL29455292

SCHEMBL29455292

Cc1cc(C)c(-c2c(C)cc(C)cc2O)c(O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.55
SELP P16109 1/20 0.55
SELE P16581 1/20 0.55
ACHE P22303 1/20 0.55
TDP1 Q9NUW8 3/20 0.48
TP53 P04637 2/20 0.48
PIM1 P11309 2/20 0.46
ALDH1A1 P00352 8/20 0.44
MAPT P10636 8/20 0.44
KDM4E B2RXH2 7/20 0.44
LMNA P02545 2/20 0.44
GAA P10253 2/20 0.44
TRPA1 O75762 1/20 0.43
KMT2A Q03164 6/20 0.43
MEN1 O00255 5/20 0.43
ELANE P08246 3/20 0.43
CYP3A4 P08684 3/20 0.43
MAPK1 P28482 3/20 0.43
ALOX15 P16050 3/20 0.43
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL851649 1.00 SELL (0.55) SELLSELPSELEACHETDP1
SCHEMBL28099808 0.90 SELL (0.46) SELLSELPSELEACHETDP1
SCHEMBL26201039 0.86 PIM1 (0.47) SELLSELPSELEACHETDP1
SCHEMBL26769093 0.84 SELL (0.65) SELLSELPSELEACHETDP1
SCHEMBL9744550 0.81 ALDH1A1 (0.50) SELLSELPSELEACHETDP1
SCHEMBL4277100 0.79 CNR1 (0.44) SELLSELPSELEACHETDP1
SCHEMBL30522730 0.79 CNR1 (0.44) SELLSELPSELEACHETDP1
SCHEMBL18838191 0.78 PIM1 (0.45) SELLSELPSELEACHETDP1
SCHEMBL317299 0.77 RAPGEF4 (0.50) SELLSELPSELEACHETDP1
SCHEMBL28859756 0.77 ALDH1A1 (0.58) SELLSELPSELEACHETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773603-B Hyperbranched polyarylethersulfone copolymer containing platinum aromatic alkynyl group and preparation method thereof 吉林大学 2023-09-05 CN claimed
US-20240400535-A1 THIOPHENE COMPOUND, METHOD FOR SYNTHESIZING SAME, AND COMPOSITION CONTAINING SAID THIOPHENE COMPOUND SHIKOKU CHEMICALS CORPORATION (JP) 2024-12-05 US disclosed
EP-3998252-B1 THIOL COMPOUNDS, SYNTHESIS METHOD THEREFOR, AND UTILIZATION OF SAID THIOL COMPOUNDS SHIKOKU CHEM (JP) 2024-04-24 EP disclosed
US-11807596-B2 Thiol compounds, synthesis method therefor, and utilization of said thiol compounds SHIKOKU CHEMICALS CORPORATION (JP) 2023-11-07 US disclosed
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound SHIKOKU CHEMICALS CORPORATION (JP) 2023-10-03 US disclosed
EP-3998252-A1 THIOL COMPOUNDS, SYNTHESIS METHOD THEREFOR, AND UTILIZATION OF SAID THIOL COMPOUNDS Shikoku Chemicals Corporation (JP) 2022-05-18 EP disclosed
US-20220112330-A1 THIOL COMPOUND, METHOD FOR SYNTHESIZING SAME, AND USES FOR SAID THIOL COMPOUND SHIKOKU CHEMICALS CORPORATION (JP) 2022-04-14 US disclosed
CN-110105176-B TMBP industrial synthesis method 甘肃泰升化工科技有限公司 2022-03-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400535-A1 THIOPHENE COMPOUND, METHOD FOR SYNTHESIZING SAME, AND COMPOSITION CONTAINING SAID THIOPHENE COMPOUND TRPA1, TMT1A, TST SELL 3170/4885SELP 1238/4885SELE 2331/4885
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound TST, TMT1A, CTH SELL 3504/4885SELP 2570/4885SELE 1046/4885
US-11807596-B2 Thiol compounds, synthesis method therefor, and utilization of said thiol compounds TMT1A, CTH, SLC7A11 SELL 371/4885SELP 591/4885SELE 152/4885
US-20220112330-A1 THIOL COMPOUND, METHOD FOR SYNTHESIZING SAME, AND USES FOR SAID THIOL COMPOUND TST, TMT1A, CTH SELL 3504/4885SELP 2570/4885SELE 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.