SCHEMBL25865220

SCHEMBL25865220

CC(C(=O)c1ccc2c(c1)OCO2)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.48
ACE P12821 2/20 0.46
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
CTSS P25774 4/20 0.45
CTSK P43235 3/20 0.45
CTSL P07711 2/20 0.45
CTSB P07858 2/20 0.45
HPGD P15428 1/20 0.45
BACE1 P56817 1/20 0.42
KDM4E B2RXH2 1/20 0.42
REN P00797 1/20 0.42
KLK5 Q9Y337 1/20 0.41
ROCK2 O75116 2/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25869329 0.89 TAAR1 (0.41) TAAR1ACETAS1R3TAS1R1CTSS
SCHEMBL24883800 0.86 ACE (0.47) ACECTSSCTSKCTSLCTSB
SCHEMBL25865289 0.84 TAS1R3 (0.43) TAAR1TAS1R3TAS1R1HPGDKDM4E
SCHEMBL29679318 0.83 ACE (0.50) ACECTSSCTSKCTSLCTSB
SCHEMBL10204542 0.83 ACE (0.50) ACECTSSCTSKCTSLCTSB
SCHEMBL27010613 0.83 ACE (0.50) ACECTSSCTSKCTSLCTSB
SCHEMBL25308745 0.83 TAS1R3 (0.41) TAAR1TAS1R3TAS1R1CTSKHPGD
SCHEMBL25308744 0.83 TAS1R3 (0.41) TAAR1TAS1R3TAS1R1CTSKHPGD
SCHEMBL25309930 0.83 TAS1R3 (0.42) TAAR1TAS1R3TAS1R1HPGDKLK5
SCHEMBL25309929 0.83 TAS1R3 (0.42) TAAR1TAS1R3TAS1R1HPGDKLK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137453-A1 PRODRUGS OF 3,4-METHYLENEDIOXY-N-METHCATHINONE AND USES THEREOF TERRAN BIOSCIENCES INC. (US) 2023-07-20 WO disclosed