SCHEMBL25865289

SCHEMBL25865289

CC(C(=O)c1ccc2c(c1)OCO2)N(C)C(=O)[C@H](C)NC(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 7/20 0.43
TAS1R1 Q7RTX1 7/20 0.43
TAAR1 Q96RJ0 1/20 0.42
KDM4E B2RXH2 2/20 0.41
NPC1 O15118 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
ADRB2 P07550 3/20 0.41
ADRB1 P08588 3/20 0.41
ADRB3 P13945 3/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25865094 0.90 TRPA1 (0.45) TAS1R3TAS1R1TAAR1KDM4ENPC1
SCHEMBL25865220 0.84 TAAR1 (0.48) TAS1R3TAS1R1TAAR1KDM4EHPGD
SCHEMBL25305808 0.83 ALDH1A1 (0.44) TAS1R3TAS1R1NPC1HPGDRAB9A
SCHEMBL25745261 0.83 ALDH1A1 (0.44) TAS1R3TAS1R1NPC1HPGDRAB9A
SCHEMBL25745258 0.83 ALDH1A1 (0.44) TAS1R3TAS1R1NPC1HPGDRAB9A
SCHEMBL25309929 0.83 TAS1R3 (0.42) TAS1R3TAS1R1TAAR1HPGDRAB9A
SCHEMBL25309930 0.83 TAS1R3 (0.42) TAS1R3TAS1R1TAAR1HPGDRAB9A
SCHEMBL30790394 0.82 TAAR1 (0.45) TAS1R3TAS1R1TAAR1KDM4ENPC1
SCHEMBL25308744 0.81 TAS1R3 (0.41) TAS1R3TAS1R1TAAR1KDM4EHPGD
SCHEMBL25308745 0.81 TAS1R3 (0.41) TAS1R3TAS1R1TAAR1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137453-A1 PRODRUGS OF 3,4-METHYLENEDIOXY-N-METHCATHINONE AND USES THEREOF TERRAN BIOSCIENCES INC. (US) 2023-07-20 WO disclosed