Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.49 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25865302 | 0.90 | TSPO (0.49) | TSPO | |
| SCHEMBL22314927 | 0.88 | KMO (0.49) | KMOTSPOALDH1A1 | |
| SCHEMBL20472706 | 0.88 | KMO (0.53) | KMOTSPOALDH1A1 | |
| SCHEMBL22314479 | 0.86 | KMO (0.63) | KMOTSPO | |
| SCHEMBL22315172 | 0.85 | KMO (0.47) | KMOTSPOALDH1A1 | |
| SCHEMBL22315037 | 0.85 | TSPO (0.51) | KMOTSPO | |
| SCHEMBL22315038 | 0.83 | KMO (0.48) | KMOTSPO | |
| SCHEMBL25865022 | 0.83 | ALDH1A1 (0.46) | KMOTSPOALDH1A1 | |
| SCHEMBL22314474 | 0.83 | KMO (0.46) | KMOTSPOALDH1A1 | |
| SCHEMBL22314928 | 0.83 | KMO (0.47) | KMOTSPOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PREC MEDICINES INC (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | KMO 2000/4885TSPO 394/4885ALDH1A1 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.