SCHEMBL3568078

SCHEMBL3568078

N#Cc1ccc(Oc2ccc(CO)cc2)cc1C#N

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.52
AR P10275 5/20 0.50
MAOB P27338 4/20 0.50
MAOA P21397 2/20 0.50
CYP19A1 P11511 2/20 0.50
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
PDE4B Q07343 1/20 0.47
NPSR1 Q6W5P4 1/20 0.45
TTR P02766 1/20 0.40
S1PR1 P21453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28662291 0.87 MAOB (0.48) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL10877056 0.86 MAOB (0.53) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL19280735 0.85 CYP19A1 (0.54) LTA4HARMAOBMAOACYP19A1
SCHEMBL25865448 0.85 AR (0.48) LTA4HARMAOB
SCHEMBL1377229 0.85 CYP19A1 (0.62) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL9472016 0.85 CYP19A1 (0.62) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL4581525 0.83 CYP19A1 (0.65) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL29390509 0.83 CYP19A1 (0.65) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL9747888 0.83 MAOB (0.50) ARMAOBMAOACYP19A1ALDH1A1
SCHEMBL3570150 0.83 MAOB (0.54) ARMAOBMAOACYP19A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378359-B2 Liquid processible diphthalonitrile monomers and resins ROLLS-ROYCE PLC (GB) 2025-08-05 US disclosed
EP-4212537-B1 LIQUID PROCESSIBLE DIPHTHALONITRILE MONOMERS AND RESINS ROLLS ROYCE PLC (GB) 2025-04-16 EP disclosed
EP-4212537-A1 LIQUID PROCESSIBLE DIPHTHALONITRILE MONOMERS AND RESINS Rolls-Royce plc (GB) 2023-07-19 EP disclosed
EP-4212537-A1 LIQUID PROCESSIBLE DIPHTHALONITRILE MONOMERS AND RESINS Rolls-Royce plc (GB) 2023-07-19 EP disclosed
US-20230212353-A1 LIQUID PROCESSIBLE DIPHTHALONITRILE MONOMERS AND RESINS ROLLS-ROYCE PLC (GB) 2023-07-06 US disclosed
US-20230212353-A1 LIQUID PROCESSIBLE DIPHTHALONITRILE MONOMERS AND RESINS ROLLS-ROYCE PLC (GB) 2023-07-06 US disclosed
US-20230212353-A1 LIQUID PROCESSIBLE DIPHTHALONITRILE MONOMERS AND RESINS ROLLS-ROYCE PLC (GB) 2023-07-06 US disclosed
CN-116332982-A Liquid processable diphthalic nitrile monomers and resins 劳斯莱斯有限公司 2023-06-27 CN disclosed
EP-3521340-A1 A PHTHALONITRILE MONOMER MODIFIED BY ORGANOPHOSPHATE FRAGMENTS, A METHOD FOR OBTAINING SAME, A BINDER BASED THEREON, AND A PREPREG Joint Stock Company Scientific and Production Association "Unichimtek" (JSC PSA "Unichimtek) (RU) 2019-08-07 EP disclosed
US-20190218235-A1 Phthalonitrile Monomer Modified with Organophosphorus Fragments, a Method of Producing thereof, a Binder Based Thereon, and a Prepreg JOINT STOCK COMPANY SCIENTIFIC AND PRODUCTION ASSOCIATION "UNICHIMTEK" (JSC PSA "UNICHIMTEK") (RU) 2019-07-18 US disclosed
EP-3211023-A1 PHTHALONITRILE MONOMER MODIFIED WITH ORGANOSILICON FRAGMENTS Joint Stock Company Scientific and Production Association "Unichimtek" (JSC PSA "Unichimtek) (RU) 2017-08-30 EP disclosed
US-7842682-B2 Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof L. Molteni & C. Dei Fratelli Alitti (IT) 2010-11-30 US disclosed
EP-1603918-B1 BORONATED METAL-PHTHALOCYANINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USE THEREOF MOLTENI & C (IT) 2008-07-30 EP disclosed
US-20080009464-A9 Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) 2008-01-10 US disclosed
US-20060135478-A1 Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) 2006-06-22 US disclosed
EP-1603918-A1 BORONATED METAL-PHTHALOCYANINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USE THEREOF L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A (IT) 2005-12-14 EP disclosed
WO-2004081014-A1 BORONATED METAL-PHTHALOCYANINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USE THEREOF L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A. (IT) 2004-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060135478-A1 Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof PBRM1, BOD1L1, PCBP1 LTA4H 4846/4885AR 1720/4885MAOB 3244/4885
US-12378359-B2 Liquid processible diphthalonitrile monomers and resins RER1, CNOT1, PNN LTA4H 929/4885AR 53/4885MAOB 3694/4885
US-20190218235-A1 Phthalonitrile Monomer Modified with Organophosphorus Fragments, a Method of Producing thereof, a Binder Based Thereon, and a Prepreg THEM6, NOTUM, PNN LTA4H 2181/4885AR 2119/4885MAOB 1907/4885
US-20080009464-A9 Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof PBRM1, BOD1L1, PCBP1 LTA4H 4846/4885AR 1720/4885MAOB 3244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.