SCHEMBL25865749

SCHEMBL25865749

NC(CCCCB(O)O)(CCNCCc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 19/20 0.66
ARG2 P78540 15/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10006146 0.95 ARG1 (0.66) ARG1ARG2
SCHEMBL25865758 0.90 ARG1 (0.54) ARG1ARG2
Hydrochloric Acid SCHEMBL2563248 0.89 ARG1 (0.76) ARG1ARG2
SCHEMBL894921 0.89 ARG1 (0.79) ARG1ARG2
Hydrochloric Acid SCHEMBL895047 0.88 ARG1 (0.77) ARG1ARG2
SCHEMBL1740434 0.87 ARG1 (0.76) ARG1ARG2
SCHEMBL27921023 0.87 ARG1 (0.76) ARG1ARG2
Hydrochloric Acid SCHEMBL895023 0.86 ARG1 (0.76) ARG1ARG2
Hydrochloric Acid SCHEMBL28034065 0.85 ARG1 (0.74) ARG1ARG2
SCHEMBL894958 0.80 ARG1 (1.00) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372499-A1 DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY THE JOHNS HOPKINS UNIVERSITY 2023-11-23 US disclosed
US-20230233696-A1 TRIANTENNARY N-ACETYLGALACTOSAMINE MODIFIED HYDROXYL POLYAMIDOAMINE DENDRIMERS AND METHODS OF USE THEREOF Ashvattha Therapeutics, Inc. (US) 2023-07-27 US disclosed
US-20230226199-A1 DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY Ashvattha Therapeutics, Inc. (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372499-A1 DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY TIE1, FLT3, FLT1 ARG1 25/4885ARG2 29/4885
US-20230233696-A1 TRIANTENNARY N-ACETYLGALACTOSAMINE MODIFIED HYDROXYL POLYAMIDOAMINE DENDRIMERS AND METHODS OF USE THEREOF FUT6, FUT5, OGT ARG1 846/4885ARG2 349/4885
US-20230226199-A1 DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY TIE1, FLT3, FLT1 ARG1 25/4885ARG2 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.