Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14873157 | 0.86 | HPGD (0.57) | EPHX1HPGDPOLBHTTTSHR | |
| SCHEMBL22289850 | 0.84 | LMNA (0.54) | EPHX1HPGDPOLBHTTTSHR | |
| SCHEMBL10667594 | 0.79 | EPHX1 (0.61) | EPHX1HPGDHTTALDH1A1EPHX2 | |
| SCHEMBL19741321 | 0.79 | EPHX1 (0.61) | EPHX1HPGDHTTALDH1A1EPHX2 | |
| SCHEMBL14424456 | 0.76 | HDAC1 (0.65) | EPHX1POLBHTTHDAC1HDAC2 | |
| SCHEMBL9528272 | 0.76 | MGLL (0.57) | EPHX1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL9533114 | 0.76 | MGLL (0.57) | EPHX1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL19741475 | 0.76 | MEN1 (0.50) | EPHX1HPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL22289535 | 0.74 | EPHX1 (0.45) | EPHX1HPGDPOLBHTTALDH1A1 | |
| SCHEMBL5940563 | 0.72 | LMNA (0.64) | HTTTSHRHDAC1HDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198059-A1 | MODULATION OF CELLULAR STRESS | The University of Queensland (AU) | 2023-06-21 | — | — | EP | disclosed |