Acrylic Acid

Acrylic Acid

SCHEMBL258661

C=CC(=O)[O-].CCCCC(C(=O)[O-])N1C(=O)C=CC1=O.[Zn+2]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.35
TSHR P16473 1/20 0.33
CA1 P00915 2/20 0.33
MGLL Q99685 4/20 0.32
PTGS1 P23219 3/20 0.32
PTGS2 P35354 3/20 0.32
FAAH O00519 2/20 0.32
THRA P10827 2/20 0.31
THRB P10828 2/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL258634 0.97 CA2 (0.35) CA2TSHRCA1MGLLPTGS1
Acrylic Acid SCHEMBL258362 0.95 CA2 (0.39) CA2CA1MGLLPTGS1PTGS2
Acrylic Acid SCHEMBL258364 0.92 CA2 (0.39) CA2CA1MGLLPTGS1PTGS2
Zinc Ion SCHEMBL258486 0.85 CA2 (0.45) CA2CA1MGLLPTGS1PTGS2
SCHEMBL258605 0.82 CA2 (0.45) CA2CA1MGLLPTGS1PTGS2
SCHEMBL2031809 0.79 TSHR (0.33) TSHRMGLLPTGS1PTGS2FAAH
SCHEMBL12094816 0.76 MGLL (0.39) CA2CA1MGLLPTGS1PTGS2
SCHEMBL43970 0.76 PTPN1 (0.42) CA2MGLLPTGS1PTGS2FAAH
SCHEMBL2219783 0.74 CA2 (0.43) CA2CA1MGLLPTGS1PTGS2
SCHEMBL2034675 0.74 MGLL (0.38) CA2CA1MGLLPTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8063161-B2 Low temperature curing acrylate and maleimide based formulations and methods for use thereof DESIGNER MOLECULES, INC. (US) 2011-11-22 US claimed
US-20100063184-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2010-03-11 US claimed
WO-2008130894-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2008-10-30 WO claimed
US-8063161-B2 Low temperature curing acrylate and maleimide based formulations and methods for use thereof DESIGNER MOLECULES, INC. (US) 2011-11-22 US disclosed
US-20100063184-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2010-03-11 US disclosed
WO-2008130894-A1 LOW TEMPERATURE CURING ACRYLATE AND MALEIMIDE BASED FORMULATIONS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2008-10-30 WO disclosed