Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 5/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723987 | 0.84 | KMT2A (0.36) | CA2CA1PTGS1PTGS2LMNA | |
| SCHEMBL43970 | 0.84 | PTPN1 (0.42) | CA2MGLLPTGS1PTGS2FAAH | |
| SCHEMBL12094816 | 0.84 | MGLL (0.39) | CA2CA1MGLLPTGS1PTGS2 | |
| SCHEMBL2034675 | 0.83 | MGLL (0.38) | CA2CA1MGLLPTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL4277446 | 0.83 | PTPN1 (0.41) | CA2MGLLPTGS1PTGS2FAAH | |
| SCHEMBL31723981 | 0.83 | MEN1 (0.35) | PTGS1PTGS2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL1704808 | 0.82 | CA1 (0.47) | CA2CA1MGLLPTGS1PTGS2 | |
| SCHEMBL6567846 | 0.82 | LMNA (0.47) | CA2CA1MGLLPTGS1PTGS2 | |
| SCHEMBL30469023 | 0.81 | CPB2 (0.39) | PTGS1PTGS2ALDH1A1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL15021865 | 0.81 | CA1 (0.46) | CA2CA1MGLLPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294707-A2 | THIOPHENE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2003-03-26 | — | — | EP | claimed |
| WO-2001098290-A2 | THIOPHENE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-27 | — | — | WO | claimed |
| US-20260000777-A1 | NECTIN-4 ANTIBODY CONJUGATES AND USES THEREOF | ARARIS BIOTECH AG (CH) | 2026-01-01 | — | — | US | disclosed |
| US-10266620-B2 | Coating agents and coated articles | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2019-04-23 | — | — | US | disclosed |
| EP-3313522-A1 | ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-B7H3-ANTIBODIES | Bayer Pharma Aktiengesellschaft (DE) | 2018-05-02 | — | — | EP | disclosed |
| US-20170081435-A1 | COATING AGENTS AND COATED ARTICLES | INNOVATIVE SURFACE TECH INC (US) | 2017-03-23 | — | — | US | disclosed |
| US-9539371-B2 | Coating agents and coated articles | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| WO-2016207104-A1 | ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-B7H3-ANTIBODIES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-29 | — | — | WO | disclosed |
| US-9518118-B2 | Anti-HER2 antibodies and immunoconjugates | GENENTECH, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| EP-2516567-B1 | COATING AGENTS AND COATED ARTICLES | INNOVATIVE SURFACE TECHNOLOGIES INC (US) | 2016-08-03 | — | — | EP | disclosed |
| US-20160096893-A1 | ANTI-HER2 ANTIBODIES AND IMMUNOCONJUGATES | GENENTECH, INC. (US) | 2016-04-07 | — | — | US | disclosed |
| US-20150359944-A1 | COATING AGENTS AND COATED ARTICLES | INNOVATIVE SURFACE TECHNOLOGIES INC (US) | 2015-12-17 | — | — | US | disclosed |
| EP-2516567-A1 | COATING AGENTS AND COATED ARTICLES | Innovative Surface Technologies, Inc. (US) | 2012-10-31 | — | — | EP | disclosed |
| US-20120258313-A1 | COATING AGENTS AND COATED ARTICLES | INNOVATIVE SURFACE TECHNOLOGIES, INC. | 2012-10-11 | — | — | US | disclosed |
| WO-2011084811-A1 | COATING AGENTS AND COATED ARTICLES | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| US-20040242854-A1 | Chemical capture reagent | GE HEALTHCARE UK LIMITED (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1402268-A2 | CHEMICAL CAPTURE REAGENT | Amersham Biosciences UK Limited (GB) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003005026-A2 | CHEMICAL CAPTURE REAGENT | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2003-01-16 | — | — | WO | disclosed |
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260000777-A1 | NECTIN-4 ANTIBODY CONJUGATES AND USES THEREOF | NECTIN4, IGSF11, VSIG8 | CA2 4563/4885CA1 2777/4885MGLL 4137/4885 |
| US-20160096893-A1 | ANTI-HER2 ANTIBODIES AND IMMUNOCONJUGATES | ERBB2, EGFR, ERBB3 | CA2 983/4885CA1 2162/4885MGLL 3990/4885 |
| US-20040242854-A1 | Chemical capture reagent | SPPL2B, PRXL2A, PLG | CA2 2273/4885CA1 1247/4885MGLL 2343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.